2-amino-3-(2-methoxyphenyl)propanoic acid → HCID 45255776, compound

HRID 2065649Notes

Reaction equation

HRID 2065649 reaction equation
Cl[C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1.[CH3:16][O:17][C:18]1[CH:29]=[CH:28][CH:27]=[CH:26][C:19]=1[CH2:20][CH:21]([C:23]([OH:25])=[O:24])[NH2:22]>>[C:23]([CH:21]([NH:22][C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1)[CH2:20][C:19]1[CH:26]=[CH:27][CH:28]=[CH:29][C:18]=1[O:17][CH3:16])([OH:25])=[O:24]

Participants

3

Reactant 2

HCID 2652722-amino-3-(2-methoxyphenyl)propanoic acidHCID 242660682,6-Dichloroquinoline-3-carboxylic acid

Product 1

HCID 45255776HCID 45255776, compound

Procedure

In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with 2-methoxy-DL-phenylalanine to provide the title compound in good yield.

Sources & evidence

ORD record
ord-38b3eaf4be5e4c5a9a34931a473b9666
Source dataset
uspto-grants-2012_10
Patent number
US08288549B2

Reaction notes

Loading…