DL-Asparagine → HCID 67360165, compound

HRID 2065650Notes

Reaction equation

HRID 2065650 reaction equation
Cl[C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1.[NH2:16][CH:17]([CH2:21][C:22]([NH2:24])=[O:23])[C:18]([OH:20])=[O:19]>>[C:22]([CH2:21][CH:17]([NH:16][C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1)[C:18]([OH:20])=[O:19])(=[O:23])[NH2:24]

Participants

3

Reactant 2

HCID 236DL-AsparagineHCID 242660682,6-Dichloroquinoline-3-carboxylic acid

Product 1

HCID 67360165HCID 67360165, compound

Procedure

In close analogy to the procedure described in Example 32, 2,6-dichloroquinoline-3-carboxylic acid is reacted with 2-amino-succinamic acid to provide the title compound in moderate yield.

Sources & evidence

ORD record
ord-d8199a27d3d14c7f8a22662be8fb04bb
Source dataset
uspto-grants-2012_10
Patent number
US08288549B2

Reaction notes

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