HCID 3767079, compound → HCID 45255965, compound

HRID 2065657Notes

Reaction equation

HRID 2065657 reaction equation
Cl[C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1.[NH2:16][CH:17]([CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[C:24]([CH2:28][CH:29]([NH2:33])[C:30]([OH:32])=[O:31])[CH:23]=1)[C:18]([OH:20])=[O:19]>>[C:12]([C:11]1[C:2]([NH:33][CH:29]([C:30]([OH:32])=[O:31])[CH2:28][C:24]2[CH:23]=[C:22]([CH2:21][CH:17]([NH:16][C:2]3[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]4[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=4)[N:3]=3)[C:18]([OH:20])=[O:19])[CH:27]=[CH:26][CH:25]=2)=[N:3][C:4]2[C:9]([CH:10]=1)=[CH:8][C:7]([Cl:15])=[CH:6][CH:5]=2)([OH:14])=[O:13]

Participants

3

Reactant 2

HCID 3767079HCID 3767079, compoundHCID 242660682,6-Dichloroquinoline-3-carboxylic acid

Product 1

HCID 45255965HCID 45255965, compound

Procedure

In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with 2-amino-3-[3-(2-amino-2-carboxy-ethyl)-phenyl]-propionic acid to provide the title compound in good yield.

Sources & evidence

ORD record
ord-e4a3bfd6f7714831ba8a7878317c3c5e
Source dataset
uspto-grants-2012_10
Patent number
US08288549B2

Reaction notes

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