HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-amino-N-methyl-3-phenylpropanamide → 6-Chloro-2-(1-methylcarbamoyl-2-phenyl-ethylamino)-quinoline-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-amino-N-methyl-3-phenylpropanamide | HCID 437612 | — |
| Reactant | 2,6-Dichloroquinoline-3-carboxylic acid | HCID 24266068 | — |
| Product | 6-Chloro-2-(1-methylcarbamoyl-2-phenyl-ethylamino)-quinoline-3-carboxylic acid | HCID 45255968 | — |
Reaction Steps
In close analogy to the procedure described in Example 32, 2,6-dichloroquinoline-3-carboxylic acid is reacted with 2-amino-N-methyl-3-phenyl-propionamide to provide the title compound in good yield. LCMS m/z 384 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288549B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-f5989e282124485e84c99494202f3ea2 |
| Source note | uspto-grants-2012_10 |