HuagongsheHuagongshe Chemistry Print Report · For research reference only
DL-Tyrosine → 6-Bromo-2-[1-carboxy-2-(4-hydroxy-phenyl)-ethylamino]-quinoline-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | DL-Tyrosine | HCID 1153 | — |
| Reactant | 6-Bromo-2-chloroquinoline-3-carboxylic acid | HCID 24266072 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 6-Bromo-2-[1-carboxy-2-(4-hydroxy-phenyl)-ethylamino]-quinoline-3-carboxylic acid | HCID 45256529 | — |
Reaction Steps
In close analogy to the procedure described in Example 1, 6-bromo-2-chloroquinoline-3-carboxylic acid is reacted with DL-tyrosine in DMSO to provide the title compound in good yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288549B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-3800546910bc4129874f9e98cd4d3cb7 |
| Source note | uspto-grants-2012_10 |