Trifluoroacetic acid → HCID 67358541, compound

Participants

Reaction Steps

Trifluoroacetic acid (5.5 g) is added dropwise to a stirred suspension of (S)-3-[4-(quinolin-4-yloxy)-phenyl]-2-tert-butoxycarbonylamino-propionic acid (0.76 g, 1.88 mmol) in THF (2 mL) while cooling with an ice bath. The mixture is stirred at rt for 3 days, then it is concentrated under reduced pressure. The residue is treated with ethyl ether to give the title compound (0.692 g, 87%) as a trifluoroacetic acid salt.

Provenance & Evidence