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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065681Generated: November 1, 2026

Sodium Hydroxide → HCID 67358658, compound

https://huagongshe.com/reaction/2065681

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant2,6-Dichloroquinoline-3-carboxylic acidHCID 24266068—
ReactantHCID 67358186HCID 67358186—
SolventDimethyl SulfoxideHCID 679—
ProductHCID 67358658HCID 67358658—

Reaction Steps

In close analogy to the procedure described in Example 32, 2,6-dichloroquinoline-3-carboxylic acid is reacted with 2-[4-(2-amino-2-carboxy-ethyl)-phenoxy]-quinoline-3-carboxylic acid ethyl ester in DMSO to provide, after hydrolysis with aqueous NaOH, the title compound in good yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288549B2
Source datasetuspto-grants-2012_10
ORD IDord-26bacdeaf7f948baab56e703da0c8486
Source noteuspto-grants-2012_10