HuagongsheHuagongshe Chemistry Print Report · For research reference only
L-Tyrosine → 2-[(S)-1-Carboxy-2-(4-hydroxy-phenyl)-ethylamino]-6,8-dichloro-quinoline-3-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | L-Tyrosine | HCID 6057 | — |
| Reactant | 2,6,8-Trichloroquinoline-3-carboxylic acid | HCID 86656379 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-[(S)-1-Carboxy-2-(4-hydroxy-phenyl)-ethylamino]-6,8-dichloro-quinoline-3-carboxylic acid | HCID 67360154 | — |
Reaction Steps
In close analogy to the procedure described in Example 1, 2,6,8-trichloroquinoline-3-carboxylic acid is reacted with L-tyrosine in H2O to provide the title compound in good yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288549B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-5fb6a4a51f584765b33e41ce73e422d3 |
| Source note | uspto-grants-2012_10 |