HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dichloroquinoline-3-carboxylic acid → HCID 67358741, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dichloroquinoline-3-carboxylic acid | HCID 24266068 | — |
| Reactant | HCID 67360868 | HCID 67360868 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 67358741 | HCID 67358741 | — |
Reaction Steps
In close analogy to the procedure described in Example 109c, 2,6-dichloroquinoline-3-carboxylic acid is reacted with (S)-2-amino-3-[4-(6-bromo-[1,8]naphthyridin-2-yloxy)-phenyl]-propionic acid (prepared by analogy to Example 109a,b) in DMSO to provide the title compound in good yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288549B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-d622b3f76dd84124add4db14adb168a3 |
| Source note | uspto-grants-2012_10 |