L-Serine → HCID 67359553, compound

HRID 2065720Notes

Reaction equation

HRID 2065720 reaction equation
Cl[C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1.[NH2:16][C@H:17]([C:20]([OH:22])=[O:21])[CH2:18][OH:19]>CS(C)=O>[C:20]([C@@H:17]([NH:16][C:2]1[C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:15])[CH:8]=2)[N:3]=1)[CH2:18][OH:19])([OH:22])=[O:21]

Participants

4

Reactant 2

HCID 5951L-SerineHCID 242660682,6-Dichloroquinoline-3-carboxylic acid

Product 1

HCID 67359553HCID 67359553, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

In close analogy to the procedure described in Example 1, 2,6-dichloroquinoline-3-carboxylic acid is reacted with L-serine in DMSO to provide the title compound in good yield.

Sources & evidence

ORD record
ord-ef8a88a4ae3d48aca9b5e033c5babf01
Source dataset
uspto-grants-2012_10
Patent number
US08288549B2

Reaction notes

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