HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butylamine → HCID 119083720, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butylamine | HCID 8007 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Heptane | HCID 8900 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 119083720 | HCID 119083720 | 65% |
Reaction Steps
Reaction of 31 (rac-Ethyl (2E)-4-(diethoxyphosphinyloxy)pent-2-enoate) (280 mg, 1.0 mmol) with nBuNH2 (198 μL, 2.0 mmol) and 8 mol % [Pd] in CH2Cl2 (10 ml) at room temperature according to Example 2. Flash chromatography (AcOEt:heptane fraction 50:50 to 55:45) yields 10 (rac-Ethyl (2E)-N-butyl-4-aminopent-2-enoate) (130 mg, 65%) as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288566B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-b7ec9d51b17d4696beaca682e69fc718 |
| Source note | uspto-grants-2012_10 |