HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → HCID 178510886, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | HCID 178453345 | HCID 178453345 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 178510886 | HCID 178510886 | 89% |
Reaction Steps
tert-butyl 2-(4-[1,1′-biphenyl]-4-yl-1H-imidazol-2-yl)ethylcarbamate (4.8 g; 0.013 mol) is stirred in 120 ml of a solution of ethyl acetate saturated in hydrochloric acid for 2 hours 30 minutes at a temperature of 55° C. The solid obtained is filtered and washed with ether. A light beige-coloured powder is obtained with a yield of 89%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288560B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-0cc11b1421ad4f019fbb0d1e7b3cbc89 |
| Source note | uspto-grants-2012_10 |