Acetyl chloride → HCID 10272950, compound

HRID 2065995Notes

Reaction equation

HRID 2065995 reaction equation
Cl.[CH:2]1[C:15]2[NH:14][C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[S:7][C:6]=2[CH:5]=[CH:4][C:3]=1[C:16]1[N:17]=[C:18]([CH2:21][NH2:22])[S:19][CH:20]=1.[C:23](Cl)(=[O:29])[CH2:24][CH2:25][CH2:26][CH2:27][CH3:28].C(Cl)(=O)C>>[CH:2]1[C:15]2[NH:14][C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[S:7][C:6]=2[CH:5]=[CH:4][C:3]=1[C:16]1[N:17]=[C:18]([CH2:21][NH:22][C:23](=[O:29])[CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[S:19][CH:20]=1

Participants

4

Reactant 3

HCID 6367Acetyl chlorideHCID 67340Hexanoyl chlorideHCID 67213853HCID 67213853, compound

Product 1

HCID 10272950HCID 10272950, compoundYield 40.7%

Procedure

This compound is prepared according to a protocol identical to that described for Example 355, with the compound of Example 362 and hexanoyl chloride respectively replacing intermediate 355.2 and acetyl chloride in Stage 355.3. The expected product is obtained in the form of a brown solid with a yield of 40.7%. Melting point: 192.0-194.0° C.

Workup

  1. customThis compound is prepared

Sources & evidence

ORD record
ord-ba8e77a71dac413793abad414eec9870
Source dataset
uspto-grants-2012_10
Patent number
US08288560B2

Reaction notes

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