Ethyl 5-bromovalerate → HCID 24849623, compound

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Reaction Steps

The title compound was prepared from ethyl 5-bromopentanoate and 4-(3,5-dichloropyridin-4-ylamino)-8-hydroxy-7-methoxy-2H-chromen-2-one (Example 29) following the procedure outlined in Example 25. 1H NMR (400 MHz, DMSO-d6): δ 9.51 (s, 1H), 8.81 (s, 2H), 7.94 (d, 1H), 7.20 (d, 1H), 4.64 (s, 1H), 4.03 (q, 2H), 3.98 (t, 2H), 3.91 (s, 3H), 2.36 (t, 2H), 1.80-1.60 (m, 4H), 1.15 (t, 3H); MS (ESI): 480.9.

Provenance & Evidence