Carbon Dioxide → HCID 23104890, compound

Participants

Reaction Steps

17 g of sulfonylbisoxazolidinone are added to 2N sodium hydroxide solution (170 ml of water for 13.6 g of NaOH) and placed under stirring. After a strong evolution of CO2, the reaction medium is stirred for 3 days at room temperature. The reaction medium is then passed through Dowex® 50WX8-200 resin (sold by Aldrich). The resin is filtered through a sinter funnel and the filtrate is concentrated under vacuum. The residue is purified by flash chromatography on silica (eluent: 8/2 EtOAc/MeOH). The volatile materials are evaporated off under vacuum to give a colourless oil (87% yield).

Provenance & Evidence