Cyclohexanol → 3-(Cyclohexyloxy)phenol

HRID 2066380Notes

Reaction equation

[C:1]([O:9][C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([OH:16])[CH:11]=1)(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4]C=1.C1(O)CCCCC1>>[CH:1]1([O:9][C:10]2[CH:11]=[C:12]([OH:16])[CH:13]=[CH:14][CH:15]=2)[CH2:2][CH2:7][CH2:6][CH2:5][CH2:4]1

Participants

Reactant 2

HCID 7966Cyclohexanol

HCID 8690Resorcinol, monobenzoate

Product 1

HCID 140669393-(Cyclohexyloxy)phenolYield 32.3%

Procedure

By using 3-hydroxyphenyl benzoate (100 mg) and cyclohexanol (54.3 μl) as starting materials, the title compound (29 mg) was obtained in the same manner as that of Reference Example 15.

Sources & evidence

ORD record: ord-a44fb75acad94d749edc69271a3080e4
Source dataset: uspto-grants-2012_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08293715B2

Reaction notes

Loading…