3-Hydroxyacetophenone → HCID 67392708, compound

HRID 2066394Notes

Reaction equation

HRID 2066394 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([C:8](=[O:10])[CH3:9])[CH:5]=[CH:6][CH:7]=1.[CH2:11]([Mg]Br)[CH3:12]>C(OCC)C>[OH:10][C:8]([C:4]1[CH:3]=[C:2]([OH:1])[CH:7]=[CH:6][CH:5]=1)([CH2:11][CH3:12])[CH3:9]

Participants

4

Reactant 2

HCID 84873-HydroxyacetophenoneHCID 178418443HCID 178418443, compound

Product 1

HCID 67392708HCID 67392708, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

By using 3′-hydroxyacetophenone (200 mg) and a 3 M solution of ethylmagnesium bromide in diethyl ether (1.5 ml) as starting materials, the title compound (124.9 mg) was obtained in the same manner as that of Reference Example 69.

Sources & evidence

ORD record
ord-0ebd2a36315e43aa864f30f90bdde386
Source dataset
uspto-grants-2012_10
Patent number
US08293715B2

Reaction notes

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