HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58117100, compound → 6-((cis)-4-Azetidin-1-yl-3-fluoro-piperidin-1-ylmethyl)-2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58117100 | HCID 58117100 | — |
| Reactant | (cis)-4-Azetidin-1-yl-3-fluoro-piperidine | HCID 66870306 | — |
| Product | 6-((cis)-4-Azetidin-1-yl-3-fluoro-piperidin-1-ylmethyl)-2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidine | HCID 58117105 | — |
Reaction Steps
Prepared according to the method used in the preparation of 2-chloro-6-(7-methyl-2,7-diaza-spiro[3.5]non-2-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine using (cis)-4-azetidin-1-yl-3-fluoro-piperidine in place of 7-methyl-2,7-diaza-spiro[3.5]nonane. The title compound was obtained as a tan solid (284 mg, 57%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293735B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-a4e039b785cf4304a6e4a648b3dae309 |
| Source note | uspto-grants-2012_10 |