HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrazino[2,1-c][1,4]oxazine, octahydro-, (9aR)- (9CI) → HCID 57506724, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrazino[2,1-c][1,4]oxazine, octahydro-, (9aR)- (9CI) | HCID 18649033 | — |
| Reactant | HCID 86650185 | HCID 86650185 | — |
| Product | HCID 57506724 | HCID 57506724 | — |
Reaction Steps
Prepared according to the method used in the preparation of (S)-4-(2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-3-isopropyl-piperazin-2-one using (R)-octahydro-pyrazino[2,1-c][1,4]oxazine in place of (S)-3-isopropyl-piperazin-2-one. The title compound was obtained as a pale yellow solid (57 mg, 62%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293735B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-c834fe2cf0d544faa2b5da2fa6a37ec8 |
| Source note | uspto-grants-2012_10 |