Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2066535Generated: October 31, 2026

(9aR)-Hexahydropyrazino[2,1-c][1,4]oxazin-4(3H)-one → HCID 58117059, compound

https://huagongshe.com/reaction/2066535

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(9aR)-Hexahydropyrazino[2,1-c][1,4]oxazin-4(3H)-oneHCID 16124470—
ReactantHCID 86650185HCID 86650185—
ProductHCID 58117059HCID 58117059—

Reaction Steps

Prepared according to the method used in the preparation of (S)-4-(2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-3-isopropyl-piperazin-2-one using (R)-hexahydro-pyrazino[2,1-c][1,4]oxazin-4-one in place of (S)-3-isopropyl-piperazin-2-one. The title compound was obtained as a tan solid (79 mg, 69%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08293735B2
Source datasetuspto-grants-2012_10
ORD IDord-f8fea36a39534544b954347e85506790
Source noteuspto-grants-2012_10