HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Indole-4-boronic acid → HCID 46239298, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Indole-4-boronic acid | HCID 2763173 | — |
| Reactant | HCID 58117126 | HCID 58117126 | — |
| Product | HCID 46239298 | HCID 46239298 | 64% |
Reaction Steps
A mixture of 2-chloro-4-morpholin-4-yl-6-[4-(tetrahydro-pyran-4-yl)-piperazin-1-ylmethyl]-thieno[3,2-d]pyrimidine (100 mg, 0.23 mmol) and indole-4-boronic acid was reacted using Suzuki coupling Method B, to give after silica chromatography, the title compound as a white solid (76 mg, 64%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293735B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-4845465614d64fdf9b9ea99c9a11376c |
| Source note | uspto-grants-2012_10 |