HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 86650546, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 86650545 | HCID 86650545 | — |
| Product | HCID 86650546 | HCID 86650546 | 87% |
Reaction Steps
Ring closure of alcohol 137 with NaH (1.6 equiv.) as in Example 2AA followed by chromatography of the product on silica gel, eluting with 0-0.5% MeOH/CH2Cl2 (foreruns) and then with 0.5-0.75% MeOH/CH2Cl2, gave additional 138 (87%) as a pale yellow solid (see above).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293734B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-035f542e6dbd4f3f8b1d9e2a2cb97453 |
| Source note | uspto-grants-2012_10 |