Acetonitrile → 2-(5-(4-(2-Morpholinoethoxy)phenyl)pyridin-2-yl)acetonitrile

HRID 2066730Notes

Reaction equation

HRID 2066730 reaction equation
F[C:2]1[N:7]=[CH:6][C:5]([C:8]2[CH:22]=[CH:21][C:11]([O:12][CH2:13][CH2:14][N:15]3[CH2:20][CH2:19][O:18][CH2:17][CH2:16]3)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[C:23](#[N:25])[CH3:24]>>[O:18]1[CH2:19][CH2:20][N:15]([CH2:14][CH2:13][O:12][C:11]2[CH:21]=[CH:22][C:8]([C:5]3[CH:4]=[CH:3][C:2]([CH2:24][C:23]#[N:25])=[N:7][CH:6]=3)=[CH:9][CH:10]=2)[CH2:16][CH2:17]1

Participants

3

Reactant 2

HCID 6342AcetonitrileHCID 441854204-(2-(4-(6-Fluoropyridin-3-yl)phenoxy)ethyl)morpholine

Product 1

HCID 441854212-(5-(4-(2-Morpholinoethoxy)phenyl)pyridin-2-yl)acetonitrile

Procedure

reacting 4-(2-(4-(6-fluoropyridin-3-yl)phenoxy)ethyl)morpholine with acetonitrile to yield 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetonitrile;

Sources & evidence

ORD record
ord-b25a875c3d104e4d8c64dd347b417b89
Source dataset
uspto-grants-2012_10
Patent number
US08293739B2

Reaction notes

Loading…