HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-(4-Bromophenoxy)ethyl)morpholine → 4-(2-(4-(6-Fluoropyridin-3-yl)phenoxy)ethyl)morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-(4-Bromophenoxy)ethyl)morpholine | HCID 2053815 | — |
| Reactant | (6-Fluoropyridin-3-yl)boronic acid | HCID 2783397 | — |
| Product | 4-(2-(4-(6-Fluoropyridin-3-yl)phenoxy)ethyl)morpholine | HCID 44185420 | — |
Reaction Steps
reacting 4-(2-chloroethyl)morpholine with 4-bromophenol to yield 4-(2-(4-bromophenoxy)ethyl)morpholine; (2) coupling 4-(2-(4-bromophenoxy)ethyl)morpholine with 6-fluoropyridin-3-yl-3-boronic acid to yield 4-(2-(4-(6-fluoropyridin-3-yl)phenoxy)ethyl)morpholine;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293739B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-f03d4726a4be4ddebaf33e89b9b903b0 |
| Source note | uspto-grants-2012_10 |