HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → 2-(5-(4-(2-Morpholinoethoxy)phenyl)pyridin-2-yl)acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | 4-(2-(4-(6-Fluoropyridin-3-yl)phenoxy)ethyl)morpholine | HCID 44185420 | — |
| Product | 2-(5-(4-(2-Morpholinoethoxy)phenyl)pyridin-2-yl)acetonitrile | HCID 44185421 | — |
Reaction Steps
reacting 4-(2-(4-(6-fluoropyridin-3-yl)phenoxy)ethyl)morpholine with acetonitrile to yield 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetonitrile; (4) converting 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetonitrile to methyl 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetate; and (5) reacting methyl 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetate with benzylamine to yield 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293739B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-1d014002f30f4e98ac6c3a5f03c9caec |
| Source note | uspto-grants-2012_10 |