HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tirbanibulin → 2-(5-(4-(2-Morpholinoethoxy)phenyl)pyridin-2-yl)acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tirbanibulin | HCID 23635314 | — |
| Reactant | 4-(2-(4-(6-Fluoropyridin-3-yl)phenoxy)ethyl)morpholine | HCID 44185420 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 2-(5-(4-(2-Morpholinoethoxy)phenyl)pyridin-2-yl)acetonitrile | HCID 44185421 | — |
Reaction Steps
In another aspect, the invention relates to a process for preparing 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide comprising the step of reacting 4-(2-(4-(6-fluoropyridin-3-yl)phenoxy)ethyl)morpholine with acetonitrile to yield 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293739B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-fbe6529dc4464f24a7770f252fea8c2b |
| Source note | uspto-grants-2012_10 |