HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromoacetate → Ethyl 2-(4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2-oxo-2H-chromen-8-yloxy)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | 4-(3,5-dichloropyridin-4-ylamino)-8-hydroxy-7-methoxy-2H-chromen-2-one | HCID 24849570 | — |
| Product | Ethyl 2-(4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2-oxo-2H-chromen-8-yloxy)acetate | HCID 24849711 | — |
Reaction Steps
The title compound was prepared from ethyl 2-bromoacetate and 4-(3,5-dichloropyridin-4-ylamino)-8-hydroxy-7-methoxy-2H-chromen-2-one (Example 29) following the procedure outlined in Example 25. 1H NMR (400 MHz, CDCl3): δ 8.61 (s, 2H), 7.43 (d, 1H), 6.98 (d, 1H), 6.60 (s, 1H), 5.12 (s, 1H), 4.84 (s, 2H), 4.28 (q, 2H), 3.99 (s, 3H), 1.31 (t, 3H); MS (ESI): 438.9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07745646B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-d5010dd840124449862f07d0c5ef28c1 |
| Source note | uspto-grants-2010_06 |