Methanol → HCID 86655008, compound

Participants

Reaction Conditions

Reaction Steps

25 mg of 16a and sulfamide (7 mg, 1.2 eq) were combined in 0.5 mL of water and 0.5 mL of methanol in a sealed vial. The mixture was stirred at 100° C. overnight then the mixture was evaporated, extracted with ethyl acetate and purified on preparative HPLC to give 17-1: LC-MS 504.2 (MH+-17), tR=5.06 (Method 5). EC50: 312 nM.

Provenance & Evidence