反应详情

To benzylamine (5.46 mL, 50 mmol), at 0° C., was added butyraldehyde (4.51 mL, 50 mmol). The mixture was warmed to room temperature and KOH (1.5 g) was added. The mix was stirred at room temperature for 15 minutes, the water was removed and 0.5 g of KOH was added. The mixture was stirred at room temperature overnight and filtered to remove the KOH to yield 6 g (74%) of 62a.

1. customthe water was removed
2. addition0.5 g of KOH was added
3. stirringThe mixture was stirred at room temperature overnight
4. filtrationfiltered
5. customto remove the KOH