Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 3301642 | HCID 3301642 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | HCID 9350311 | HCID 9350311 | 92% |
Reaction Steps
671 Milligrams of ethyl 5-methyl-4-oxo-2-piperidinomethyl-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylate was suspended in 8 mL of 0.5N sodium hydroxide, stirred at 80° C. for 2 hours, and allowed to cool off. The reaction liquid was neutralized with 2N hydrochloric acid, and the precipitate was recovered by filtration and dried, to provide 565 mg (92%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08293754B2 |
|---|
| Source dataset | uspto-grants-2012_10 |
|---|
| ORD ID | ord-3dce37557b6449b8bb14e277307fcf44 |
|---|
| Source note | uspto-grants-2012_10 |
|---|
