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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2066946Generated: October 31, 2026

4-Piperidone → HCID 57821257, compound

https://huagongshe.com/reaction/2066946

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-PiperidoneHCID 33721—
ReactantEthyl 2-(chloromethyl)-5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylateHCID 2339310—
ProductHCID 57821257HCID 57821257—

Reaction Steps

Using ethyl 2-chloromethyl-5-methyl-4-oxo-3,4-dihydrothieno-[2,3-d]pyrimidine-6-carboxylate and piperidin-4-one, a substitution reaction was carried out similarly to later appearing Production Example 21. Successively the reaction product was hydrolyzed similarly to Example 33, without intervening isolation of the reaction product, to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08293754B2
Source datasetuspto-grants-2012_10
ORD IDord-6458857288b84a6e8b2f5b9b3bcb74b0
Source noteuspto-grants-2012_10