HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67524990, compound → HCID 67525403, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67524990 | HCID 67524990 | — |
| Catalyst | Nickel | HCID 935 | — |
| Product | HCID 67525403 | HCID 67525403 | 40% |
Reaction Steps
Hydrogenation of the alkyne 9 (0.055 g, 0.18 mmol) using BER/Ni catalyst gave 40% 27, 5% of the saturated compound and 55% of starting material. The mixture was separated by reverse-phase HPLC chromatography (20% acetonitrile/80% water 20 min isocratic program) to give 27 (15 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293796B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-2fc2d4d5866f4833a338be1118feba38 |
| Source note | uspto-grants-2012_10 |