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HRID2067236

反应详情

EQUATION

反应方程式

HRID 2067236 的结构方程式

REACTANTS

反应物

2
结构：C#CC(C)(C)O
HCID8258

2-Methyl-3-butyn-2-ol

C5H8O

结构：Cc1ccc(N=[N+]=[N-])cc1C(=O)c1ccc(Nc2ccc(F)cc2F)cc1Cl
HCID86605529

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(-n2cc(C(C)(C)O)nn2)cc1C(=O)c1ccc(Nc2ccc(F)cc2F)cc1Cl
HCID11511387

未命名化合物

PROCEDURE

实验过程

The reaction was carried out similarly as described in the preparation of compound 116, using compound 434 (0.125 mmol) and 2-methyl-but-3-yn-2-ol (0.125 mmol). The crude product was purified by continuous gradient flash chromatography using EtOAc/petroleum ether (40-60) 30:70 to 70:30 as the eluent to afford the title compound.

WORKUP

后处理

  1. customThe crude product was purified by continuous gradient flash chromatography