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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2067262Generated: October 30, 2026

(5-Amino-2-methyl-phenyl)-[2-chloro-4-(4-trifluoromethyl-phenylamino)-phenyl]-methanone → (5-Amino-2-methyl-phenyl)-[2-chloro-4-(4-methoxy-phenylamino)-phenyl]-methanone

https://huagongshe.com/reaction/2067262

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(5-Amino-2-methyl-phenyl)-[2-chloro-4-(4-trifluoromethyl-phenylamino)-phenyl]-methanoneHCID 68419668—
Reactant[2-Chloro-4-(4-methoxy-phenylamino)-phenyl]-(2-methyl-5-nitro-phenyl)-methanoneHCID 68420442—
Product(5-Amino-2-methyl-phenyl)-[2-chloro-4-(4-methoxy-phenylamino)-phenyl]-methanoneHCID 68418362—

Reaction Steps

The reaction was carried out similarly as described in the preparation of compound 415, using compound 446 (0.31 mmol). The crude product was used without any further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08293772B2
Source datasetuspto-grants-2012_10
ORD IDord-0aae58f83b5047f5bccb91904355dde3
Source noteuspto-grants-2012_10