3'-Aminoacetophenone → HCID 11626640, compound

Participants

Reaction Steps

The reaction was carried out similarly as described in the preparation of compound 148, using compound 452 (0.13 mmol) and 1-(3-amino-phenyl)-ethanone (0.13 mmol). The crude product was purified by continuous gradient flash chromatography using MeOH/DCM/petroleum ether (40-60) 0:50:50, 0:100:0 and 5:95:0 as the eluent to afford the title compound as yellow solid. 13C NMR (CDCl3) δ 197.8, 197.1, 147.1, 146.3, 143.3, 142.3, 141.2, 138.5, 137.1, 135.3, 134.7, 132.3, 129.8, 128.5, 124.8, 123.2, 121.5, 120.0, 119.9, 119.6, 118.7, 111.8, 61.6, 28.7, 26.7, 22.2, 19.6

Provenance & Evidence