3-Chloro-2-methylaniline → HCID 11597810, compound

Participants

Reaction Steps

The reaction was carried out similarly as described in the preparation of compound 148, using compound 452 (0.13 mmol) and 3-chloro-2-methyl-phenylamine (0.13 mmol). The crude product was purified by continuous gradient flash chromatography using MeOH/DCM/petroleum ether (40-60) 0:50:50, 0:100:0 and 5:95:0 as the eluent to afford the title compound as yellow solid. 13C NMR (CDCl3) δ 197.0, 148.6, 146.3, 143.5, 142.5, 139.9, 137.0, 135.7, 135.5, 134.6, 132.2, 130.9, 127.5, 127.1, 126.0, 122.4, 121.3, 119.9, 119.9, 117.8, 111.1, 61.6, 28.7, 22.3, 19.5, 15.0

Provenance & Evidence