m-Aminoacetanilide → HCID 11554573, compound

Participants

Reaction Steps

The reaction was carried out similarly as described in the preparation of compound 148, using compound 452 (0.13 mmol) and N-(3-amino-phenyl)-acetamide (0.13 mmol). The crude product was purified by continuous gradient flash chromatography using NH3(aq.)/MeOH/DCM 0:0:100, 1:9:90 as the eluent to afford the title compound as yellow solid. 13C NMR (DMSO-d6) δ 196.1, 168.2, 147.9, 145.6, 142.4, 142.0, 141.2, 140.1, 135.1, 135.0, 134.3, 131.9, 129.3, 126.0, 120.6, 120.2, 118.2, 117.6, 114.2, 112.7, 111.1, 110.0, 60.1, 29.1, 24.0, 22.1, 18.7

Provenance & Evidence