反应详情

The reaction was carried out similarly as described in the preparation of compound 414, using compound 402 (2.82 mmol) and 3-methyl-phenylamine (3.10 mmol). The crude product was purified by continuous gradient flash chromatography using EtOAc/petroleum ether (40-60) 5:95 to 30:70 as the eluent to afford the title compound.

1. customThe crude product was purified by continuous gradient flash chromatography