2,5-Difluoroaniline → HCID 11511108, compound

Participants

Reaction Steps

The reaction was carried out similarly as described in the preparation of compound 148, using compound 471 (0.13 mmol) and 2,5-difluoro-phenylamine (0.13 mmol). The crude product was purified by flash chromatography using MeOH/DCM 1:20 as the eluent to afford the title compound. 13C NMR (CDCl3) δ 194.9, 158.8 (d), 150.2 (d), 146.3 (d), 140.4, 138.4, 135.2, 134.8, 133.5, 132.7, 129.9, 122.5, 121.0, 119.9, 117.9, 116.6 (dd), 114.5, 109.5 (dd), 107.1 (d), 61.6, 28.7, 20.1

Provenance & Evidence