Ethyl 4-methyl-2-(2-oxo-3-phenylimidazolidin-1-yl)thiazole-5-carboxylate → HCID 58031555, compound

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Reaction Steps

Following the procedure as described in Example 6, making variations as required to replace ethyl 4-methyl-2-(2-oxo-3-phenylimidazolidin-1-yl)thiazole-5-carboxylate with ethyl 2-(3-(4-chlorobenzyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxylate, the title compound was obtained in 96% yield: 1H NMR (300 MHz, DMSO-d6) δ 7.45 (d, J=7.2 Hz, 2H), 7.29 (d, J=7.2 Hz, 2H), 4.39 (s, 2H), 4.06-3.91 (m, 2H), 3.51-3.39 (m, 2H), 2.53 (s, 3H); MS (ES+) m/z 352.2 (M+1), 354.2 (M+1).

Provenance & Evidence