5-Bromoindole → HCID 59317744, compound
Reaction equation
Br[C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)NC=C2.[Br:11][C:12]1[CH:13]=[C:14]2[C:18](=[CH:19][CH:20]=1)[NH:17][C:16]([CH3:21])=[CH:15]2>>[Br:11][C:12]1[CH:13]=[C:14]2[C:18](=[CH:19][CH:20]=1)[N:17]([C:2]1[CH:3]=[CH:4][CH:8]=[CH:9][CH:10]=1)[C:16]([CH3:21])=[CH:15]2Participants
3
Procedure
The same reaction was performed as in Reference Example 1 except for using, instead of the 5-bromoindole, 5-bromo-2-methylindole to afford the above-identified compound (4.2 g).
Workup
- customThe same reaction
Sources & evidence
- ORD record
- ord-4b1ab38d0b90408fa574e2d1b2988afd
- Source dataset
- uspto-grants-2012_10
- Patent number
- US08293781B2
Reaction notes
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