HRID2067722

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C[Si](C)(C)CCOCn1ccnc1CC(CN)Cc1nccn1COCC[Si](C)(C)C

HCID68956828

未命名化合物

结构：CC(C)CN1CCC2(CC1)CCN(Cc1ccc(C=O)cc1)C2

HCID86630102

未命名化合物

PRODUCTS

生成物

结构：CC(C)CN1CCC2(CC1)CCN(Cc1ccc(CNCC(Cc3nccn3COCC[Si](C)(C)C)Cc3nccn3COCC[Si](C)(C)C)cc1)C2

HCID68953172

未命名化合物

收率 43.3%

PROCEDURE

实验过程

Except for using the compound (200 mg) produced in Example 29 in place of 8-isobutyl-2,8-diazaspiro[4.5]decane and using the compound (135 mg) produced in Example 27 in place of 4-(diethoxymethyl)benzaldehyde, the same operation as in Example 26 was performed to obtain the title compound (142 mg) having the following physical properties.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-33c320b9facb49c898d51d079e7be302
来源数据集: uspto-grants-2012_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08293896B2
来源说明: uspto-grants-2012_10

反应 SMILES

[CH3:1][Si:2]([CH3:31])([CH3:30])[CH2:3][CH2:4][O:5][CH2:6][N:7]1[CH:11]=[CH:10][N:9]=[C:8]1[CH2:12][CH:13]([CH2:16][C:17]1[N:18]([CH2:22][O:23][CH2:24][CH2:25][Si:26]([CH3:29])([CH3:28])[CH3:27])[CH:19]=[CH:20][N:21]=1)[CH2:14][NH2:15].[CH2:32]([N:36]1[CH2:54][CH2:53][C:39]2([CH2:43][N:42]([CH2:44][C:45]3[CH:52]=[CH:51][C:48]([CH:49]=O)=[CH:47][CH:46]=3)[CH2:41][CH2:40]2)[CH2:38][CH2:37]1)[CH:33]([CH3:35])[CH3:34]>>[CH2:32]([N:36]1[CH2:54][CH2:53][C:39]2([CH2:43][N:42]([CH2:44][C:45]3[CH:46]=[CH:47][C:48]([CH2:49][NH:15][CH2:14][CH:13]([CH2:16][C:17]4[N:18]([CH2:22][O:23][CH2:24][CH2:25][Si:26]([CH3:28])([CH3:27])[CH3:29])[CH:19]=[CH:20][N:21]=4)[CH2:12][C:8]4[N:7]([CH2:6][O:5][CH2:4][CH2:3][Si:2]([CH3:1])([CH3:30])[CH3:31])[CH:11]=[CH:10][N:9]=4)=[CH:51][CH:52]=3)[CH2:41][CH2:40]2)[CH2:38][CH2:37]1)[CH:33]([CH3:35])[CH3:34]