HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → (4-Bromo-2,6-dimethyl-phenyl)-carbamic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Ethyl chloroformate | HCID 10928 | — |
| Reactant | 4-Bromo-2,6-xylidine | HCID 90549 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | (4-Bromo-2,6-dimethyl-phenyl)-carbamic acid ethyl ester | HCID 11644748 | 97% |
Reaction Steps
Ethyl chloroformate (0.55 g, 0.48 mL, 5 mmol) was added to a solution of 4-bromo-2,6-dimethyl-phenylamine (1.0 g, 5 mmol) in acetonitrile (20 mL). The reaction mixture was stirred at reflux for 16 hours. Water was added to the mixture and the precipitate formed collected to give the title compound as a powder (1.32 g, 97% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293911B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-63d6b0f45d654e21b0836fe8daa9fb01 |
| Source note | uspto-grants-2012_10 |