反应详情

To a suspension of 6-chloropyridazine-3-carbaldehyde (2.50 g, 17.5 mmol) in 30 mL of methanol (30 mL) at 0° C. was added sodium borohydride (0.26 g, 7.02 mmol). The reaction mixture was warmed to room temperature. After 2 hours, the reaction mixture was concentrated in vacuo and triturated with 20% MeOH in dichloromethane to provide (6-chloropyridazin-3-yl)methanol.

1. concentrationthe reaction mixture was concentrated in vacuo
2. customtriturated with 20% MeOH in dichloromethane