3-Fluorobenzyl isocyanate → HCID 58055090, compound

HRID 2067995Notes

Reaction equation

HRID 2067995 reaction equation
Cl[C:2]1[CH:3]=[C:4]([CH:17]=[CH:18][C:19]=1Cl)[CH2:5][NH:6][C:7]([NH:9][C:10]1[S:11][CH:12]=[C:13]([CH2:15][Cl:16])[N:14]=1)=[O:8].[F:21]C1C=C(C=CC=1)CN=C=O>>[Cl:16][CH2:15][C:13]1[N:14]=[C:10]([NH:9][C:7]([NH:6][CH2:5][C:4]2[CH:17]=[CH:18][CH:19]=[C:2]([F:21])[CH:3]=2)=[O:8])[S:11][CH:12]=1

Participants

3

Reactant 2

HCID 6434993-Fluorobenzyl isocyanateHCID 58055096HCID 58055096, compound

Product 1

HCID 58055090HCID 58055090, compound

Procedure

Prepared by same procedure described for Intermediate 2, using 3-fluorobenzyl isocyanate. 1H-NMR (ppm, DMSO-d6): 10.70 (bs, 1H), 7.36 (dd, 1H), 7.07 (m, 4H), 4.63 (s, 2H), 4.34 (d, 2H).

Workup

  1. customPrepared by same procedure

Sources & evidence

ORD record
ord-845688b435aa463e9ebdd14b472428f2
Source dataset
uspto-grants-2012_10
Patent number
US08293919B2

Reaction notes

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