HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-butyl hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate → tert-butyl 5-(3-(4-fluorophenylsulfonyl)quinolin-8-yl)hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-butyl hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate | HCID 44474550 | — |
| Reactant | 3-(4-Fluorophenylsulfonyl)-8-iodoquinoline | HCID 68729790 | — |
| Product | tert-butyl 5-(3-(4-fluorophenylsulfonyl)quinolin-8-yl)hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate | HCID 25196384 | 69% |
Reaction Steps
The title compound was prepared by analogy to the procedure of Example 1.3, except using 3-(4-fluorophenylsulfonyl)-8-iodoquinoline and tert-butyl hexahydropyrrolo[3,4-b]pyrrole-1(2H)-carboxylate. 250 mg (69%) of the title compound were obtained as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293913B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-c757c59b93ad48fab5d6b3f9e781916f |
| Source note | uspto-grants-2012_10 |