HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(3-Fluorophenylsulfonyl)-8-iodoquinoline → 8-(5-benzyl-1H-pyrrolo[3,4-c]pyridin-2(3H,3aH,4H,5H,6H,7H,7aH)-yl)-3-(3-fluorophenylsulfonyl)quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(3-Fluorophenylsulfonyl)-8-iodoquinoline | HCID 67314157 | — |
| Reactant | 5-benzyloctahydro-1H-pyrrolo[3,4-c]pyridine-2,5-diium chloride | HCID 86647688 | — |
| Product | 8-(5-benzyl-1H-pyrrolo[3,4-c]pyridin-2(3H,3aH,4H,5H,6H,7H,7aH)-yl)-3-(3-fluorophenylsulfonyl)quinoline | HCID 68725500 | — |
Reaction Steps
0.367 g of 8-(5-benzyl-1H-pyrrolo[3,4-c]pyridin-2(3H,3aH,4H,5H,6H,7H,7aH)-yl)-3-(3-fluorophenylsulfonyl)quinoline were prepared by analogy to the method of Example 27 by coupling of 3-(3-fluorophenylsulfonyl)-8-iodoquinoline with 5-benzyloctahydro-1H-pyrrolo[3,4-c]pyridine-2,5-diium chloride
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08293913B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-b81f8429fab347d7bb3903c3885a655e |
| Source note | uspto-grants-2012_10 |