HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bis(2-bromoethyl) ether → 8-(2-(2-Bromoethoxy)ethoxy)-4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2H-chromen-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bis(2-bromoethyl) ether | HCID 21521 | — |
| Reactant | 4-(3,5-dichloropyridin-4-ylamino)-8-hydroxy-7-methoxy-2H-chromen-2-one | HCID 24849570 | — |
| Product | 8-(2-(2-Bromoethoxy)ethoxy)-4-(3,5-dichloropyridin-4-ylamino)-7-methoxy-2H-chromen-2-one | HCID 24849843 | — |
Reaction Steps
The title compound was prepared from 2-bromoethyl ether and 4-(3,5-dichloropyridin-4-ylamino)-8-hydroxy-7-methoxy-2H-chromen-2-one (Example 29) following the procedure outlined in Example 25. 1H NMR (400 MHz, DMSO-d6): δ 9.51 (s, 1H), 8.81 (s, 2H), 7.94 (d, 1H), 7.20 (d, 1H), 4.64 (s, 1H), 4.13 (m, 2H), 3.93 (s, 3H), 3.80-3.74 (m, 4H), 3.55 (t, 2H); MS (ESI): 502.7.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07745646B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-8b51279addd34ead9c54528bafafd35d |
| Source note | uspto-grants-2010_06 |