Potassium Carbonate → HCID 86642454, compound

Participants

Reaction Steps

Subsequently, the 2-deoxy-2-iodo-3,4,6-tri-O-acetyl-1-O-triethylsilyl-β-D-glucopyranose (III) (0.7 g) was dissolved in the mixture of chloroform:methanol (7:3 v/v) (15 mL). Potassium carbonate (4 g) was added, and reaction mixture was stirred at room temperature until substrate deacetylation has been completed. Inorganic salts were filtered off and solvents were evaporated. Such obtained product was purified by column chromatography (SilicaGel 60, Merck) using chloroform and chloroform:methanol 99:1 as eluents, to give (0.1 g) of 2-deoxy-2-iodo-1-O-triethylsilyl-β-D-glucopyranose (VI) (yield 20%).

Provenance & Evidence