HCID 67234282, compound → HCID 67234106, compound

Participants

Reaction Steps

Dissolve 4-benzyloxy-N-[1-[[(4R)-5,6-dihydro-4H-imidazo[1,2-a][1]benzazepin-4-yl]carbamoyl]cyclopropyl]benzamide (145 mg, 294.37 μmoles) in ethanol (20 mL) and hydrogenate on a Parr shaker with 10% Pd/C (22.8 mg, 10.71 μmoles) for 18 hours (60 psi, ambient temperature). Filter off the catalyst and concentrate the filtrate under reduced pressure to give the title compound (107 mg, 90%) as a white solid: MS (m/z): 403 (M+1).

Provenance & Evidence